Antimicrobial Activity of Root Extracts of Albizia chevalieri on some selected Medical Isolates

Abstract

Albizia chevalieri is a tree with a long list of folklore therapeutic claims many bacterial species have been reported to develop resistance to antibiotics. Hencethe need to search for natural products remedy to this problem cannot be over emphasized. This study was aimed to determine the antimicrobial effect of the plant. The plant material was extracted with distilled water, chloroform, acetone and methanol. Phytochemical screening was carried out to detect for the presence of phytoconstituents. Agar well diffusion was employed to determine the antimicrobial activity, where the inhibitory level of the extracts Was found to be promising nearing the positive control,Escherichia coli being inhibited the following concentrations of (17, 15, 18, and 16% Staphylococcus aureusbeing inhibited (29, 19, 14 and 11% inhibition) and Candida albicans being inhibited 15, 8, 12 and 10% inhibition). Phytochemical screening of the root extracts of Albizia chevalieri revealed the presence of secondary metabolites in good amounts. Being four extracts showed broad spectrum of activity. Low minimum inhibitory concentration, minimum bactericidal concentration (125 and 250mg/ml respectively) and minimum fungicidal concentration values ranging from 31.25 and 62.5mg/ml while a high Minimum Inhibitory Concentration, Minimum Bactericidal Concentration and Minimum Fungicidal Concentration values ranges from 125 and 250mg/ml respectively. With this result, it shows that Acetone extract and Methanol extract have more effect on the bacterial isolates than Chloroform extract and distilled water extract. Therefore, the plant can be explored by pharmaceutical industries for drugs production and also in textile industries for making dyes.